Itchy Armpits as a Sign of Lymphoma or Breast Cancer

You may already be aware of common symptoms of cancer, which might include rashes, a lump in your breast, or unexplained bruises, but did you know having itchy armpits can also be a sign of cancer? Itchy armpits, also known as pruritis, could be related to other health conditions, including allergic reactions and eczema, but in rare cases, it could mean something more serious.

“Some cancers … may result in having itchy armpits,” said Danielle Leonardo, MD, an internal medicine specialist, oncologist, and writer at My BC Team. “These include breast cancer with axillary node involvement, lymphoma involving the lymph nodes of the armpits, or other blood disorders like leukemia which may present with general skin itchiness.”

One type of breast cancer that can cause itchy armpits is inflammatory breast cancer. It is called “inflammatory” as it causes swollen, red, or inflamed breasts.

This rare and aggressive type of breast cancer creates a rash on the affected breast, leaving the breast with pink, dark red or purple skin and texture that resembles an orange peel. In addition, the nipples may invert or flatten on the affected breast. Itchiness, rash, and tenderness are early signs of inflammatory breast cancer. Inflammatory breast cancer accounts for one to five percent of all breast cancers diagnosed in the United States.

Itchy armpits may also occur after receiving breast cancer treatment. Armpit discomfort may arise after receiving a lumpectomy, mastectomy, or lymph node removal. In addition to itchiness, patients may have swollen, tender, or numb armpits.

Other cancer treatments that might cause itchy armpits include:

• Chemotherapy

• Immunotherapy

• Radiation therapy

If you are experiencing itching under your arms throughout cancer treatment, discuss your symptoms with your doctor, as they may be able to adjust your treatment plan.

Additionally, itchy armpits can be a sign of lymphoma. Lymphoma is a type of blood cancer that affects the lymphatic system. Lymphoma begins in the lymphocytes, a type of white blood cell.

People with lymphoma may experience swelling in the armpits that lasts for several weeks. This symptom is more common among patients with Hodgkin lymphoma than those with non-Hodgkin lymphoma. It’s unclear what causes itchiness in the armpits, but it may be due to chemicals released by the immune system as a reaction to the lymphoma.

Individuals with itchy armpits and other signs of lymphoma – such as swelling of lymph nodes in your neck, armpits or groin, and persistent fatigue – should seek professional medical advice from their doctor.

Aside from breast cancer, breast cancer treatments, and lymphoma, there are several other reasons why you may have itchy armpits.

Allergic reactions

You might have discomfort under your arms if you’ve come into contact with something you’re allergic to. “Allergies to certain substances, like detergents or fabrics, can also cause an itchy sensation,” said Garvit Chitkara, MBBS, DNB, a breast cancer surgeon and senior consultant at Nanavati Max Institute of Cancer Care. If you’re unsure of your allergies, speak with your doctor to see if you can take an allergy test.

Skin conditions

Several skin conditions can also cause itchy armpits. “Other than being a potential symptom of cancer, itchy armpits can also occur due to skin irritations, such as contact dermatitis or psoriasis,” said Dr. Chitkara.

Some skin conditions that might cause itchiness in the armpits include:

• Hidradenitis suppurtiva

• Eczema

• Contact dermatitis

• Atopic dermatitis

• Seborrheic dermatitis

• Psoriasis

• Folliculitis

There are treatments available for many benign skin conditions to relieve itchiness, alongside other symptoms that cause pain and discomfort.

Deodorants and antiperspirants

Certain skincare products in your daily hygiene routine, like deodorants and antiperspirants, may cause itchy armpits.

Common ingredients in deodorants and antiperspirants that can cause itching are:

• Aluminum

• Fragrances

• Parabens

• Lanolin

• Propylene glycol

Check the ingredients of your personal care products to see if they contain anything you might be allergic to. “Avoid using deodorants with fragrances or perfumes, if they are known to cause irritation,” Dr. Chitkara said.

Menopause

Menopause occurs twelve months after a woman’s last menstrual cycle. This condition decreases estrogen levels. Estrogen is a hormone that plays a significant role in maintaining the reproductive system. Menopause can cause dry skin, leading to itchiness across the body, including the armpits.

Infections

Infections may cause unpleasant itching under your arm. “Fungal or bacterial infections affecting the axillary area can also cause itchy armpits,” said Dr. Leonardo. Itching is a symptom of common infections like chickenpox, ringworm, athlete’s feet, and vaginal thrush or thrush in men.

Diabetes

Itchy armpits may be a sign of diabetes, a common chronic condition. Dry skin is a common experience for people with diabetes, and can lead to itchiness in the armpits.

If cancer is not the cause, here’s how to address itchy armpits.

Use skincare products that won’t cause irritation

Opt for deodorants, antiperspirants, and other products that won’t irritate your armpits. “Itchy armpits can be prevented by practicing good hygiene, like regularly taking a bath using mild, fragrance-free soaps, and hypoallergenic deodorants,” said Leonardo.

Do a self-examination

Examining your armpits can help you detect any noticeable skin changes or lumps that could be a sign of cancer or other health conditions. If you detect skin changes or lumps, then you should see your primary doctor or a dermatologist for evaluation, Dr. Leonardo said.

Get medical care

Seeking medical care for treatment is crucial if you’re experiencing itchiness or other symptoms lasting several weeks or more. “Your doctor may recommend anti-itch creams or topical medications to reduce inflammation and itching,” Dr. Chitkara said. “If there is an underlying medical condition causing the itching, then they will be able to provide appropriate treatment for that as well.”

In rare instances, itchy armpits may indicate cancer, which is why you should take it seriously – especially if it coincides with other potential symptoms of cancer. “If you are experiencing any other concerning symptoms such as lumps or swelling under the skin, swollen lymph nodes, unexplained weight loss, and persistent fatigue, then you should seek medical advice immediately,” Dr. Chitkara said.

However, in most cases, itchy armpits can occur due to allergies, skin conditions, skincare products, menopause, infections, and diabetes.