JAK2 Negative? Understanding Gene Mutations and Treatment for MPNs

There’s plenty of information about MPNs and JAK2 mutations, including treatments that are appropriate for those with the mutation. But what if you’re JAK2 negative? Dr. Brady Stein from Northwestern Medicine explains gene mutations related to MPNs and MPN diagnosis. He shares which treatments tend to be effective for both JAK2 negative and JAK2 positive patients and discusses the recent discovery of the calreticulin (CALR) as it relates to MPN diagnosis and treatment.

Produced in association with the Robert H. Lurie Comprehensive Cancer Center of Northwestern University.

This article was originally published October 16, 2014 and most recently updated September 11, 2019.
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